Well known as a sculptor, Meadmore began his career as a designer. His furniture was sold at Marion Hall Best’s showrooms and his lighting design shown at the 1956 Melbourne Olympics Arts Festival alongside the work of designers such as Grant Featherston. Meadmore ran Max Hutchinson's Gallery A, Melbourne, in the late 1950s. In 1963 he moved to New York, where he concentrated primarily on his work as a sculptor.